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Jun 23, - But how exactly do these drugs affect people's sexual experiences, and what are their downsides? Weed: Higher Libido and More Orgasms in Psychopharmacology found that cocaine use increases sexual desire. Jul 20, - You might have heard that cocaine enhances sexual experiences, but known effect as an aphrodisiac, significantly increasing sexual drive. With all things considered, using cocaine does not actually help sexual stamina.